(2S)-2-[(2S)-2-{[(tert-butoxy)carbonyl]amino}-3-methylbutanamido]-5-(carbamoylamino)pentanoic acid - Names and Identifiers
(2S)-2-[(2S)-2-{[(tert-butoxy)carbonyl]amino}-3-methylbutanamido]-5-(carbamoylamino)pentanoic acid - Physico-chemical Properties
Molecular Formula | C16H30N4O6
|
Molar Mass | 374.43 |
Density | 1.183±0.06 g/cm3(Predicted) |
Boling Point | 624.8±55.0 °C(Predicted) |
pKa | 3.44±0.10(Predicted) |
Storage Condition | 2-8℃ |
In vitro study | ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker. |
(2S)-2-[(2S)-2-{[(tert-butoxy)carbonyl]amino}-3-methylbutanamido]-5-(carbamoylamino)pentanoic acid - Introduction
Boc-Val-Cit-OH is a chemical compound whose chemical name is N-tert-butoxycarbonyl-L-valyl-L-citrulline acid. The following is a description of the nature, use, preparation and safety information of the Boc-Val-Cit-OH:
Nature:
Boc-Val-Cit-OH is a white solid, soluble in some organic solvents such as dimethyl sulfoxide (DMSO) and methanol. It is a compound with amino acid sequence and has high chemical stability.
Use:
Boc-Val-Cit-OH are commonly used as intermediates in organic synthesis, especially in the field of peptide synthesis. It can be used to synthesize peptides, proteins and other bioactive molecules, and has a wide range of applications.
Preparation Method:
The preparation method of the Boc-Val-Cit-OH can be achieved by the following steps:
1. First, N-tert-butoxycarbonyl-L-valine (Boc-Val-OH) is reacted with N,N'-dipropylcarbodiimide (DCCI), n-tert-butoxycarbonyl-L-valine dipropylcarbodiimide Ester is produced.
2. Next, the product is reacted with hydroxylamine hydrochloride to produce Boc-Val-Cit-OH.
Safety Information:
Boc-Val-Cit-OH there are certain security risks, please take appropriate protective measures during operation. Avoid direct contact with skin and eyes, and wear appropriate protective gloves, goggles and protective clothing. Avoid inhaling dust or gas during operation. If accidental exposure occurs, flush the affected area and seek medical help.
This is only a brief introduction to the Boc-Val-Cit-OH. If more detailed information is needed in a specific application, please refer to the relevant academic literature or consult a professional.
Last Update:2024-04-09 21:01:54